A novel murine model of late-phase reaction of immediate hypersensitivity

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A novel murine model of late-phase reaction of immediate hypersensitivity

We describe here a novel experimental model of late-phase reaction of immediate hypersensitivity developed in mice. It consists of introducing small fragments of heat-coagulated hen egg white into the subcutaneous tissue of mice. After 14 days, animals challenged with purified ovalbumin into the footpad presented an immediate swelling of the paw peaking at 30 min, followed by two peaks of swell...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 1997

ISSN: 0962-9351,1466-1861

DOI: 10.1080/09629359791820